Acute ocular toxoplasmosis presenting in a patient with immunodeficiency — including HIV infection — requires a specific clinical approach that differs from management in immunocompetent hosts.
This protocol addresses patients with an immunodeficiency or immunocompromised state, such as HIV infection. Both the treatment strategy and the avoidance of certain agents that would otherwise be considered are shaped directly by the patient's immune status.
Management centres on an antimicrobial combination regimen, with systemic corticosteroids generally avoided; maintenance antimicrobial therapy is continued for as long as the patient remains immunocompromised. The complete structured regimen is available via the full protocol below.
DOI: 10.1007/s10792-021-01994-9