Acute Necrotizing Ulcerative Gingivitis
ICD-10 A69.0; A69.1 · ICD-11 1C1H

Treatment of Severe Acute Necrotizing Ulcerative Gingivitis with Fever and Lymphadenopathy

Clinical Scenario

This protocol addresses severe acute necrotizing ulcerative gingivitis that has progressed to systemic involvement, marked by fever and regional lymphadenopathy. This presentation is clinically distinct from mild or uncomplicated ANUG and requires a more comprehensive management approach.

Condition Features

Severe cases with fever and lymphadenopathy represent a sub-population where local periodontal disease is accompanied by systemic signs. This systemic involvement influences the treatment strategy beyond what would be used for uncomplicated presentations.

Treatment Approach (Partial Overview)

Management combines mechanical debridement of the gingiva with systemic antibiotic therapy. The complete protocol specifies the instrumentation method, antibiotic selection, and the full regimen — including any alternative agents.

Full regimen details available via the structured protocol below.

Treatment Goals

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1902/jop.1986.57.3.141
Severe cases with fever and lymphadenopathy may benefit by antibiotic therapy in addition to debridement.
Goldhaber and Giddon support this approach to therapy, but they also suggest the use of antibiotics, principally penicillin, in the treatment of advanced cases.
Recent English dental literature supports the use of antibiotics in the treatment of ANUG, and investigators using metronidazole in double-blind clinical studies found it as effective as penicillin in causing remission of the clinical symptoms of ANUG.
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