Treatment of Acute Myocarditis in Lymphocytic, Virus-Negative Myocarditis
Acute myocarditis presenting as the lymphocytic, virus-negative subtype is a clinically specific pattern. Identifying this subtype directly shapes the first-line treatment decision.
Clinical Scenario
Lymphocytic myocarditis with no identified viral aetiology (virus-negative). This subtype distinction is central to selecting the appropriate management approach.
Treatment Approach — Partial Overview
First-line management of this condition centres on corticosteroid therapy, with the regimen stratified by disease severity. The complete severity-stratified algorithm, dosing, and tapering schedule are available in the full protocol →
References
DOI: 10.1093/eurheartj/ehaf192
- Lymphocytic myocarditis (virus-negative)
- Non-severe: prednisone 1 mg/kg/day p.o. then tapered
- Severe: i.v. methylprednisolone 7–14 mg/kg/day for 3 days, then 1 mg/kg/day p.o.
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