Treatment of Acute Myocarditis in Giant-Cell Myocarditis
This protocol addresses the treatment of acute myocarditis occurring in the specific clinical context of giant-cell myocarditis, a presentation that calls for a defined first-line approach.
Clinical Scenario
The patient presents with acute myocarditis in the setting of giant-cell myocarditis. This specific context determines the treatment strategy outlined in the protocol.
Treatment Approach
First-line management is built around corticosteroid therapy combined with an immunosuppressive agent, with the approach calibrated to disease severity.
Agent selection, the severity-based dosing strategy, and the full treatment sequence are detailed in the complete protocol.
References
DOI: 10.1093/eurheartj/ehaf192
- Giant-cell myocarditis
- Non-severe: prednisone 1 mg/kg/day p.o. then tapered
- Severe: i.v. methylprednisolone 7–14 mg/kg/day for 3 days, then 1 mg/kg/day p.o. + immunosuppressive (azathioprine or mycophenolate mofetil, cyclosporine)