Acute lymphoblastic leukemia (ALL) requires a prolonged, structured treatment course. Following induction and consolidation, a dedicated maintenance phase is a standard and essential component of management, recommended for all patients.
Management includes a continuous oral chemotherapy backbone during maintenance, supplemented by periodic prophylaxis directed at the central nervous system. The complete regimen — including the specific agents, their sequencing, and the full duration framework — is detailed in the structured protocol below.
DOI: 10.1182/blood.2023023568