When a patient with acute kidney injury (AKI) needs renal replacement therapy (RRT) and also has hemodynamic instability, acute brain injury, increased intracranial pressure, or generalised brain edema, the choice of RRT modality matters. These comorbidities shape which approach is appropriate.
This protocol addresses AKI patients requiring RRT in the presence of hemodynamic instability, or those with acute brain injury, increased intracranial pressure, or generalised brain edema. Standard intermittent RRT may not be the preferred option in this population.
Evidence favours a continuous modality of renal replacement therapy over standard intermittent RRT in these specific situations — but the full clinical protocol, practical parameters, and decision algorithm remain in the structured regimen below.
DOI: 10.1159/000339789
We suggest using CRRT, rather than standard intermittent RRT, for hemodynamically unstable patients.
We suggest using CRRT, rather than intermittent RRT, for AKI patients with acute brain injury or other causes of increased intracranial pressure or generalized brain edema.
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