Acute Epididymo-Orchitis
ICD-10 N45 · ICD-11 GB02.0

Treatment of Acute Epididymo-Orchitis with Purulent Urethral Discharge When Gonorrhoea Is Likely

This protocol covers sexually transmitted epididymo-orchitis in patients where gonorrhoea is considered a likely causative organism. The approach differs from standard epididymo-orchitis management and is driven by the presence of specific clinical risk factors.

Risk Factors That Indicate This Protocol

Treatment Overview (Partial)

When gonorrhoea is considered likely, management requires a combination antibiotic regimen that provides optimal cover against gonococcal infection, together with general supportive measures. The complete agent selection, dosing, and sequencing are available in the full protocol.

Clinical target: Improvement in symptoms at three days.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1177/0956462417699356

In patients where gonorrhoea is considered likely (see risk factors above) azithromycin should be added to ceftriaxone and doxycycline to provide optimal antibiotic cover.

General advice: analgesia, rest and scrotal support.

At three days if there is no improvement in symptoms, the patient should be seen for clinical review and the diagnosis should be reassessed.

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