Acute appendicitis
ICD-10 K35ICD-11 DB10.0

What is the treatment of acute uncomplicated appendicitis without abscess or perforation?

This protocol addresses adult and pediatric patients presenting with acute appendicitis where preoperative assessment shows no evidence of abscess or perforation — the uncomplicated form of the disease.

Uncomplicated appendicitis is defined as cases without preoperative evidence of abscess or perforation. This distinction drives the management pathway and the evidence base behind it.
Operative management is the recommended approach. Evidence-based guidance addresses the question of surgical timing — whether the operation should be performed immediately or after a delay — though the full criteria and conditional recommendations are detailed in the complete protocol.
References
DOI: 10.1007/s00464-024-10813-y
  • Uncomplicated appendicitis was defined as cases without preoperative evidence of abscess or perforation.
  • The panel suggests that adult and pediatric patients with uncomplicated appendicitis be managed operatively (conditional recommendation based on low certainty of evidence in adults and very low certainty of evidence in pediatrics).
  • The panel suggests that adult and pediatric patients with uncomplicated appendicitis may undergo either delayed (>12h) or immediate operation (<12h) (conditional recommendation, based on very low certainty of evidence).
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