This page addresses a specific clinical scenario: perforating folliculitis arising in a patient currently receiving a molecular-targeted drug (kinase inhibitor), where a causal relationship between the drug and the skin finding is strongly suspected.
Perforating folliculitis developing during molecular-targeted drug (kinase inhibitor) treatment. The literature documents numerous cases associating this dermatologic presentation with this drug class when a causal link is strongly suspected.
When a causal relationship is strongly suspected, management centres on the molecular-targeted drug (kinase inhibitor) currently in use. The structured protocol outlines the recommended course of action for this situation.
Complete clinical decision steps available via the link below.
DOI: 10.1111/1346-8138.15647
There are many articles indicating that perforating folliculitis might have occurred during the use of molecular-targeted drugs (kinase inhibitors).
In cases where a causal relationship is strongly suspected, we suggest discontinuing the molecular-targeted drug (kinase inhibitor) and consider changing to another drug.
View source ↗