This protocol targets adults who develop acquired reactive perforating collagenosis — defined by the transepidermal elimination of collagen fibers — with onset of skin lesions after age 18 and the characteristic presentation of umbilicated papules or nodules bearing a central adherent keratotic plug.
The structured protocol for this condition includes ultraviolet (UV) therapy as a treatment modality. The complete clinical decision algorithm — including selection criteria, sequencing, and additional considerations — is available through the full protocol.
DOI: 10.1111/1346-8138.15647
Acquired reactive perforating collagenosis presents with transepidermal elimination of collagen fibers.
In 1994, Faver et al. published the diagnostic criteria as meeting all of the following: (i) histopathological findings of elimination of necrotic basophilic collagen tissue into a cup-shaped epidermal depression; (ii) clinical presentation of umbilicated papules or nodules with a central adherent keratotic plug; and (iii) onset of skin lesions after the age of 18 years.
We suggest that UV therapy be considered as a treatment for acquired reactive perforating collagenosis.
View source ↗