Treatment of Acetaminophen-Induced Acute Liver Injury When Transplantation Criteria Are Met
Clinical Scenario
Acetaminophen-induced acute liver injury can progress to a severity where standard medical management is insufficient. In patients whose condition reaches specific established prognostic thresholds, emergency escalation becomes the central management decision.
Treatment Approach — partial overview
For patients with acetaminophen-induced acute liver injury who fulfil established prognostic criteria, emergency liver transplantation is the intervention considered — carried out via a specific surgical approach described in the full protocol.
The exact prognostic criteria, procedural pathway, and complete decision algorithm are available in the full structured regimen below.
References
DOI: 10.1016/j.jhep.2016.12.003
- Transplantation should be considered in those patients fulfilling Clichy or Kings College criteria (evidence level II-2, grade of recommendation 1).
- The classical procedure when performing LTx is orthotopic LTx using a liver graft from a cadaveric donor.
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