Abdominal actinomycosis
ICD-10 A42.1 · ICD-11 1C10.1

Mild Monomicrobial Abdominal Actinomycosis Not Resolving with Penicillin V

This protocol covers the management step taken when initial oral therapy for mild monomicrobial abdominal actinomycosis has failed to achieve resolution of the infection.

Clinical Scenario

Monomicrobial actinomycosis of mild severity, in a patient without penicillin allergy. Management of monomicrobial infections is stratified by severity: infection is considered severe when it involves an organ in a life-threatening manner or affects multiple organs.

Previous Treatment — Goal Not Achieved

Initial oral therapy with penicillin V, continued until resolution of infection (typically 6–12 months), did not achieve resolution of the actinomycosis infection. The protocol below describes the management step that follows this treatment failure.

Next-Step Management (Partial Overview)

When infection progresses or becomes complicated, a surgical approach forms the basis of next-step management — the full protocol details the specific indications, approach, and complete management algorithm.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.5772/intechopen.104698

For patients with monomicrobial infections, treatment can be divided base on mild versuss severe disease.

If the infection involves an organ causing a life threatening disease or multiple organs, it is considered severe.

When infection complicates with abscess and fistula formation, surgical management and drainage is warranted, especially in life threatening presentations.

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