This protocol applies to AA amyloidosis in patients who have an underlying chronic infection. The persistent infectious process sustains the systemic inflammatory response that drives AA protein deposition, making the source of infection central to the management strategy.
The structured protocol directs therapy at the underlying infectious cause. The approach involves targeted antimicrobial treatment selected according to the responsible organism. The primary clinical goal is:
Remission of amyloidosis-associated nephrotic syndromeThe complete evidence-based regimen, organism-specific selection criteria, and full clinical algorithm are available in the protocol below.
DOI: 10.2147/CLEP.S39981
Remission of amyloidosis-associated nephrotic syndrome has also been achieved with tuberculostatic treatment.
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